Strategy #1: Ask your doctor if generics will work for you. This won't work for everybody, but many popular drugs are available in generic form for a dramatically reduced price.
Strategy #2: Check out the possibility of getting free prescription drugs. Go to the Partnership for Prescription Assistance www.pparx.org. This website helps you find drugs that are eligible for financial assistance. These "patient assistance programs" are generally for low income households and you may have to verify your income and medical expenses.